Asian Journal of Hospital Pharmacy

Assessment of Risk Factors In Chronic Kidney Disease Patients At Tertiary Care Hospital In Nellore

Fri, 14 Aug 2026 00:00:00 -0400

The purpose of this study is to evaluate the different risk variables in Nellore patients with chronic renal disease. Method: From November 2025 to March 2026, a six-month prospective observational study was carried out. The patient's demographic chart and kidney health assessment questionnaire were used to gather the data, which was then examined using descriptive statistics. The chi-square test and correlation were used to determine the primary risk factor. Results: According to the current study, the main risk factor for both males and females is hypertension (p=0.0001), however other risk factors such diabetes, obesity, and alcohol use are also important. It was discovered that the average age of CKD patients was 46.24 for females and 49.02 for men. Conclusion: In both males and females with chronic renal disease, hypertension was identified as the primary significant risk factor. However, compared to women, men are more likely to have hypertension as a risk factor for chronic renal disease. These chronic kidney diseases are also influenced by other risk factors such diabetes mellitus, smoking, alcohol, obesity, hypotension, stroke, urinary tract infections, drug-induced nephrotoxicity, etc. The prevalence of end-stage renal disease can be decreased by identifying the main risk factors.

Pre-Operativeand Post-Operative Antibiotic Strategiesfor Prevention of Surgical Site Infection: A Focus on Infection Control Protocol in the Surgery Ward

Mangilal T, Tara Nasreen Atiya, Tarannum Rahela, Muttangi Mercy, Amena Mumtaz — Sun, 09 Aug 2026 00:00:00 -0400

Surgical site infections (SSIs) are among the most common healthcare-associated infections and remain a significant cause of postoperative morbidity, prolonged hospitalisation, and increased healthcare costs. This prospective observational study evaluated the effectiveness of pre-operative and post-operative antibiotic strategies in preventing SSIs among patients undergoing general surgical procedures. The study was conducted over six months in the Department of General Surgery at SVS Medical College and Hospital, Mahabubnagar, and included 100 patients. Data on patient demographics, comorbidities, type of surgery, antibiotic selection, timing of administration, dosage, duration of therapy, and postoperative outcomes were collected from medical records and clinical observations. Patients were monitored throughout their hospital stay for the development of SSIs. The mean age of the study population was approximately 44 years, with males constituting the majority of participants. The overall incidence of SSIs was 35%, including 31 cases of superficial SSI and 4 cases of deep SSI, while no organ/space infections were observed. Higher infection rates were identified among patients with diabetes mellitus and those undergoing major surgical procedures. Ceftriaxone-based regimens were the most commonly prescribed prophylactic antibiotics. Patients who developed SSIs had longer hospital stays than those without infections. The findings demonstrate that appropriate perioperative antibiotic prophylaxis, including correct antibiotic selection, timely administration, and adherence to recommended guidelines, plays a vital role in reducing the incidence of surgical site infections, improving postoperative recovery, and enhancing the quality of surgical care.

Evaluation of Dual Antiplatelet Therapy in Patients with Myocardial Infarction: Safety and Efficacy Analysis

Sat, 15 Aug 2026 00:00:00 -0400

Myocardial infarction (MI) is a major cardiovascular emergency associated with myocardial ischemia and necrosis resulting from reduced coronary blood flow. Dual antiplatelet therapy (DAPT), consisting of aspirin combined with a P2Y12 inhibitor, is routinely used to prevent recurrent ischemic events, although bleeding remains an important safety concern. This prospective observational study evaluated the prescribing patterns, efficacy, safety, medication adherence, and adverse drug reactions associated with DAPT among patients with MI. The study was conducted over six months in the Department of Cardiology of a tertiary care teaching hospital and included 100 patients receiving DAPT. Demographic, clinical, treatment, adherence, and adverse drug reaction data were collected using a structured case record form. Medication adherence was assessed using the Morisky Medication Adherence Scale, while adverse drug reactions were evaluated using the WHO–UMC causality assessment scale. The mean patient age was 62.68 ± 10.15 years, 65% were aged above 60 years, and 75% were male. Aspirin plus clopidogrel was the most frequently prescribed regimen (43%), followed by aspirin plus prasugrel (31%) and aspirin plus ticagrelor (26%). Moderate adherence predominated, while adverse drug reactions occurred in 70% of patients, mainly bleeding-related events. Individualized DAPT selection based on thrombotic and bleeding risks may improve safety, adherence, and secondary prevention outcomes following MI.